Publications
Recent Peer Reviewed Articles:
Doughty, A., Keane, G., Wadley A.J., Mahoney B., Bueno A.A and Coles S.J. (2024) Plasma thioredoxin, thioredoxin reductase and peroxiredoxin-4 in acute coronary syndrome identifies high risk patients: a clinical observation. International Journal of Cardiology doi/10.1016/j.ijcard.2024.131888
Carvalho, J.F., Coles, S.J and Bueno, A.A. (2023) Vitamin B12 (cobalamin) supplementation for the management of autoimmune rheumatic diseases: potential indications and opportunity for future research. Rheumatology International doi.org/10.1007/s00296-023-05490-4
Hillier, J., Allcott, G.J., Guest, L.A., Heaselgrave, W., Tonks, A., Conway, M.E., Cherry, A.L. and Coles S.J. (2022) The BCAT1 CXXC motif provides protection against ROS in acute myeloid leukaemia cells. Antioxidants doi/10.3390/antiox11040683
Rastogi, N., Baker, S., Man, S., Uger, R., Wong, M., Coles, S.J., Hodges, M., Gilkes, A., Knapper, S., Darley, R. and Tonks, A. (2021) Use of an anti-CD200 blocking antibody improves immune responses to AML in vitro and in vivo. British Journal of Haematology doi/10.1111/bjh.17125
Wadley, A.J., Cullen T, Vautrinot, J, Keane G, Bishop, N.C. and Coles, S.J. (2020) High intensity interval exercise increases the frequency of peripheral PD-1+ CD8+ Central memory T-cells and soluble PD-L1 in Humans Brain Behavior and Immunity – Health doi.org/10.1016/j.bbih.2020.100049
Heaselgrave, W., Hamad, A., Coles, S.J. and Hau, S. (2019) In vitro evaluation of the inhibitory effect of topical ophthalmic agents on Acanthamoeba viability Translational Vision Science & Technology 8(5), 2164-2591
Wadley, A.J., Keane, G., Cullen, T., James, L., Vautrinot, J., Davies, M., Hussey, B., Hunter, D.J., Mastana, S.S., Holiday, A., Petersen, S.V., Bishop, N.C., Lindley, M.R. and Coles, S.J. (2019) Characterisation of extracellular redox enzyme concentrations in response to exercise in humans Journal of Applied Physiology doi.org/10.1152/japplphysiol.00340.2019
Wadley, A.J., Morgan, R.G., Heesom, K.J., Hole, P.S and Coles, S.J. (2018) Detecting intracellular thiol redox stat in leukaemia and heterogeneous immune cell populations: an optimized protocol for digital flow cytometers MethdosX 5, 1473-1483
Morgan, R.G., Chambers, A.C., Legge, D.N., Coles, S.J., Greenhough, A and Williams, A.C. (2018) Optimized delivery of siRNA into 3D tumour spheroid cultures in situ Scientific Reports 8(1), 7952
Coles, S.J. (2018) Targeting the immune checkpoint in cancer: is this a viable treatment option for AML? Open Access Journal of Oncology and Medicine 1(2), 1-2
Wadley, A.J., Holliday, A., Morgan, R.G., Heesom, K.J., Aldred, S., Peters, D.M., Bueno, A.A and Coles, S.J. (2018) Preliminary evidence of reductive stress in human cytotoxic T-cells following exercise Journal of Applied Physiology doi.org/10.1152/ japplphysiol.01137.2017
Coles, S.J and Wadley, A.J. (2017) Can BCAT1 expression level help predict disease progression in chronic lymphocytic leukaemia. Canc Oncol Open Access J 1(1), 1-5
Wadley, A.J., Aldred, S and Coles, S.J. (2016) An unexplored role for Peroxiredoxin in exercise-induced redox signalling? Redox Biology 8, 51-58
Coles, S.J., Gilmour, M., Reid, R., Knapper, S., Man, S., Tonks, A. and Darley R.L. (2015) The immunosuppressive ligands PD-L1 and CD200 are linked in AML immunosuppression: identification of a new immunotherapeutic synapse. Leukaemia DOI: 10.1038/leu.2015.62.
Agathanggelou, A., Weston, V.J., Perry, T., Davies, N.J., Skowronska, A., Payne, D.T., Fossey, J.S., Oldreive, C.E., Wei, W., Pratt, G., Parry, H., Oscier, D., Coles, S.J., Hole, P.S., Darley, R.L., McMahon, M., Hayes, J.D., Moss, P., Stewart, G., Taylor, M.R. and Stankovic, T. (2015) Targeting the ATM-null phenotype in chronic lymphocytic leukaemia with pro-oxidants. Haematologica DOI: 10.3324/haematol.2014.115170.
Book Sections:
Wadley, A.J. and Coles, S.J. (2022) Time to ‘couple’ redox biology with exercise immunology in Oxidative Eustress in Exercise Immunology ISBN: 9781003051619
Wadley, A.J., Morgan R.G., Darley R.L., Hole, P.S and Coles, S.J. (2019) Using flow cytometry to detect and measure intracellular thiol redox status in viable T cells from heterogeneous populations Methods in Molecular Biology 1990, 53-70
Conferences:
Oct 2020 – EuroLeuk (poster presentation)
Apr 2020 – British Society for Haematology Annual Meeting (poster presentation), abstract available in BJHaem
Dec 2018(1) – American Society of Haematology Annual Meeting (poster presentation) abstract available in Blood
Dec 2018 (2) – American Society of Haematology Annual Meeting (poster presentation) abstract available in Blood
Dec 2014 – American Society of Haematology Annual Meeting (poster presentation) abstract available in Blood